Methoxyamine (hydrochloride)
Catalogue number:
HY-Y0958-5g
Supplier:
Size:
5 g
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
593-56-6
Purity:
98.0
Molecular Formula:
CH6ClNO
Molecular Weight:
83.52
Mass Spectrometry:
Reference Materials
Alternative Names:
O-Methylhydroxylamine (hydrochloride)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents[1][2].