Volasertib
Catalogue number:
HY-12137-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
755038-65-4
Purity:
99.87
Molecular Formula:
C34H50N8O3
Molecular Weight:
618.81
Mass Spectrometry:
Reference Materials
Alternative Names:
BI 6727
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC50s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models[1][2].