VU0422288
Catalogue number:
HY-110190-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1630936-95-6
Purity:
99.94
Molecular Formula:
C17H11Cl2N3O2
Molecular Weight:
360.19
Mass Spectrometry:
Reference Materials
Alternative Names:
ML396
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
VU0422288 (ML396) is a positive allosteric modulator of group III mGluRs. VU0422288 inhibits mGluRs with EC50s of 125 nM, 146 nM, and 108 nM for mGluR4, mGluR7, and mGluR8, respectively in calcium mobilization assays. VU0422288 reverses deficits in contextual fear memory, social recognition, and apneas in Rett syndrome (RTT) model mice[1][2].