This product is for research use only and is not for human consumption or therapeutic use.
Molecular Formula:
C10H7NO3
Molecular Weight:
189.17
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
IOX1, a chemical probe, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 µM, 2.3 µM, 1.8 µM, 0.1 µM and 1.4 µM, respectively[1][2]. IOX1 also inhibits ALKBH5[3].