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IOX1

Catalogue number:
HY-12304-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

5852-78-8

Purity:

99.89

Molecular Formula:

C10H7NO3

Molecular Weight:

189.17

Mass Spectrometry:

Reference Materials

Product Description:

IOX1, a chemical probe, is a potent broad‐spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 µM, 2.3 µM, 1.8 µM, 0.1 µM and 1.4 µM, respectively[1][2]. IOX1 also inhibits ALKBH5[3].