FOSL1 degrader 1
Catalogue number:
HY-162723-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
99.47
Molecular Formula:
C58H69N5O18
Molecular Weight:
1124.19
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
FOSL1 degrader 1 (4) is a T-5224-PROTAC, potently degrade FOSL1 (AP-1) to suppress cancer stemness gene expression in HNSCC. FOSL1 degrader 1 (4) effectively eliminate HNSCC cancer stem cells to inhibit tumor growth through degrading FOSL1. FOSL1 degrader 1 (4) displays around 30- to 100-fold increased potency over T-5224 (Pink: T-5224 (HY-12270); Black: Linker (HY-130200); Blue: Pomalidomide (HY-10984))[1].