Pyridone 6
Catalogue number:
HY-14435-2mg
Supplier:
Size:
2 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
457081-03-7
Purity:
98.20
Molecular Formula:
C18H16FN3O
Molecular Weight:
309.34
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases.