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R 59-022

Catalogue number:
HY-107613-1ml
Supplier:
Size:
1 ml
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

93076-89-2

Purity:

99.82

Molecular Formula:

C27H26FN3OS

Molecular Weight:

459.58

Mass Spectrometry:

Reference Materials

Alternative Names:

DKGI-I; Diacylglycerol kinase inhibitor I

Product Description:

R 59-022 (DKGI-I) is a DGK inhibitor (IC50: 2.8 µM). R 59-022 inhibits the phosphorylation of OAG to OAPA. R 59-022 is a 5-HT Receptor antagonist, and activates protein kinase C (PKC). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits phosphatidic acid production in neutrophils[1][2][3][4]. 10mM