Terfenadine
Catalogue number:
HY-B1193-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
50679-08-8
Purity:
99.98
Molecular Formula:
C32H41NO2
Molecular Weight:
471.67
Mass Spectrometry:
Reference Materials
Alternative Names:
(±)-Terfenadine; MDL-991
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM[1]. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9[2]. 10mM