BMS-P5 (free base)
Catalogue number:
HY-137655A-1ml
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1550371-22-6
Purity:
99.93
Molecular Formula:
C27H32N6O2
Molecular Weight:
472.58
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
BMS-P5 free base is a selective and orally active peptidylarginine deiminase 4 (PAD4) inhibitor with an IC50 of 98 nM. BMS-P5 free base shows selective for PAD4 over PAD1, PAD2, and PAD3. BMS-P5 free base blocks multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation and delays progression of MM in a syngeneic mouse model[1]. 10mM