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SAR405

Catalogue number:
HY-12481-1ml
Supplier:
Size:
1 ml
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1523406-39-4

Purity:

99.74

Molecular Formula:

C19H21ClF3N5O2

Molecular Weight:

443.85

Mass Spectrometry:

Reference Materials

Product Description:

SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity[1][2]. 10mM