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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1971920-73-6
Purity:
99.79
Molecular Formula:
C26H25N5O3
Molecular Weight:
455.51
Mass Spectrometry:
Reference Materials
Alternative Names:
SAR442168; PRN2246
- Data sheet: View or download
- MSDS: View or download
Product Description:
Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS)[1][2]. Supplied size: 1mg