Mazdutide
Catalogue number:
HY-P3375-1mg
Supplier:
Size:
1 mg
Product is available in:
CAS Number:
2259884-03-0
Purity:
99.94
Molecular Weight:
4563.06
Alternative Names:
IBI-362; LY-3305677; OXM-3
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR). Mazdutide binds human and mouse GCGR (Ki: 17.7 nM and 15.9 nM, respectively) and GLP-1R (Ki: 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets (EC50: 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D)[1][2][3].