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mPGES1-IN-7

Catalogue number:
HY-118282-1mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1268709-57-4

Purity:

99.78

Molecular Formula:

C23H34N4O

Molecular Weight:

382.54

Mass Spectrometry:

Reference Materials

Product Description:

mPGES-1-IN-2 (compound III) is a benzimidazole-based mPGES-1 inhibitor that also inhibits adipophysin PGD synthase (I-PGDS) (5 µM, IR=60 %). mPGES-1-IN-2 reduces PGE2 production and tends to reduce levels of other prostaglandins. mPGES-1-IN-2 effectively inhibits acute inflammation in an air sac model stimulated by Carrageenan (HY-125474) in mice[1].