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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1228280-29-2
Purity:
99.24
Molecular Formula:
C18H16N4O2S
Molecular Weight:
352.41
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
Product Description:
KY-05009 is an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM. KY-05009 pharmacologically inhibits TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells. KY-05009 inhibits the protein expression of TNIK and transcriptional activity of Wnt target genes and induces apoptosis in cancer cells. KY-05009 exerts anti-cancer activity[1]. Supplied size: 1mg