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Thalidomide-Propargyne-PEG2-COOH

Catalogue number:
HY-138777-10mg
Supplier:
Size:
10 mg
Product is available in:
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2797619-65-7

Purity:

98.73

Molecular Formula:

C21H20N2O8

Molecular Weight:

428.39

Mass Spectrometry:

Reference Materials

Product Description:

Thalidomide-Propargyne-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Thalidomide-Propargyne-PEG2-COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.