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CAS Number:
2650557-72-3
Molecular Formula:
C27H28FN5
Molecular Weight:
441.54
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- MSDS: View or download
- Protocol: View or download
Product Description:
NCOA4-9a inhibits ferroptosis by reducing the amount of bioavailable intracellular ferrous iron through disrupting the nuclear receptor coactivator 4 (NCOA4)−FTH1 (Ferritin) protein−protein interaction. NCOA4-9a inhibits Erastin (HY-15763)-induced ferroptosis, with EC50 of 0.29 µM in HT22 cells[1].