Trontinemab
Catalogue number:
HY-P9999-5mg
Supplier:
Size:
5 mg
Product is available in:
Applications:
Neuroscience-Neurodegeneration
Target:
Amyloid-β
Alternative Names:
RG6102; RO-7126209
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human TFR1[1][2][3][4].