Cremophor EL-36
Catalogue number:
HY-401424-50g
Supplier:
Size:
50 g
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
61791-12-6
Alternative Names:
Polyoxyethylene(36) Castor Oil; PEG-36 Castor Oil
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- MSDS: View or download
- Protocol: View or download
Product Description:
Cremophor EL-36 is a nonionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). The functions of Cremophor EL-36 include: 1) affecting pharmacokinetics by encapsulating drugs in micelles, changing drug distribution and clearance; 2) activating the complement system and inducing allergic reactions; 3) binding to lipoproteins and interfering with lipid metabolism. Cremophor EL-36 increases drug solubility through micellization, while mediating toxicity through complement activation and lipoprotein interactions[1][2].