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DOCK2-IN-1

Catalogue number:
HY-153128-10mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£436.00 Special price until 31 Dec 2025
Normal price £484.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

4590-86-7

Mass Spectrometry:

Reference Materials

Product Description:

DOCK2-IN-1 (compound 3), a CPYPP (HY-110100) analogue, is an inhibitor of DOCK2 as well (IC50=19.1 µM). DOCK2-IN-1 binds to DOCK2 DHR-2 domain in a reversible manner to inhibits its catalytic activity. DOCK2-IN-1 blocks the activation of both chemokine receptor- and antigen receptor-mediated Rac in lymphocytes. DOCK2-IN-1 significantly suppresses chemotactic response and T cell activation[1].