PBRM1-BD2-IN-5
Catalogue number:
HY-151532-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2819989-61-0
Purity:
99.75
Molecular Formula:
C15H13ClN2O
Molecular Weight:
272.73
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
PBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1.5 µM and 3.9 µM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0.26 µM for PBRM1-BD2. PBRM1-BD2-IN-5 reduces the binding of full-length PBRM1 within the PBAF complex in cell lysates to acetylated histone peptide. PBRM1-BD2-IN-5 can be used to research anticancer[1].