Berubicin
Catalogue number:
HY-14942-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
677017-23-1
Purity:
87.76
Molecular Formula:
C34H35NO11
Molecular Weight:
633.64
Mass Spectrometry:
Reference Materials
Alternative Names:
RTA 744 (free base); WP 744 (free base); WP 769
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Berubicin (RTA 744 free base) is a Doxorubicin (HY-15142A) analog that can cross the blood-brain barrier. Berubicin inhibits P-gp and MRP1-mediated efflux and suppresses glioblastoma multiforme (GBM). Berubicin exerts toxic effects on leukemia cells by activating nuclear factor κB (NF-κB) and induces apoptosis in neuroblastoma cells. Berubicin can be used in the study of tumors related to the nervous system[1][2][3][4][5].