(S)-Bleximenib (oxalate)
Catalogue number:
HY-148669B-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
98.37
Molecular Formula:
C34H52FN7O7
Molecular Weight:
689.82
Mass Spectrometry:
Reference Materials
Alternative Names:
(S)-JNJ-75276617 (oxalate); (S)-Menin-MLL inhibitor 24 (oxalate)
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
(S)-Bleximenib (oxalate) is a S-Enantiomer of Bleximenib oxalate (HY-148669A). Bleximenib (JNJ-75276617) oxalate is an orally active and selective menin-KMT2A inhibitor, with IC50 values of 0.1 nM, 0.045 nM, and ≤0.066 nM for humans, mice, and dogs, respectively. Bleximenib oxalate can inhibit the proliferation and induce apoptosis and differentiation of tumor cells. Bleximenib oxalate can be used in the research of tumors such as leukemia[1].