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JPS014 (TFA)

Catalogue number:
HY-145815A-25mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
Purity:

98.40

Molecular Formula:

C48H60F3N7O9S

Molecular Weight:

968.09

Mass Spectrometry:

Reference Materials

Product Description:

JPS014 TFA is a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimeras (PROTAC). JPS014 TFA degrades class I histone deacetylase (HDAC). JPS014 TFA is potent HDAC1/2 degrader correlated with greater total differentially expressed genes and enhanced apoptosis in HCT116 cells[1].