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3'-Azido-3'-deoxyadenosine

Catalogue number:
HY-131802-1mg
Supplier:
Size:
1 mg
£121.00
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This product is no longer available to order.
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

58699-62-0

Mass Spectrometry:

Reference Materials

Product Description:

3'-Azido-3'-deoxyadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3'-Azido-3'-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.