K-Ras ligand-Linker Conjugate 6
Catalogue number:
HY-130991-50mg
Supplier:
Size:
50 mg
Product is available in:
£711.00
Special price until 31 Dec 2025
Normal price £790.00
Shipping is calculated in checkout
Normal price £790.00
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2378261-89-1
Product Description:
K-Ras ligand-Linker Conjugate 6 incorporates a ligand for K-Ras recruiting moiety, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). K-Ras ligand-Linker Conjugate 6 can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523), which is potent PROTAC K-Ras degrader that exhibits ≥70% degradation efficacy in SW1573 cells[1].