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Azido-PEG5-alcohol

Catalogue number:
HY-130211-5g
Supplier:
Size:
5 g
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

86770-68-5

Purity:

98.29

Molecular Formula:

C10H21N3O5

Molecular Weight:

263.29

Product Description:

Azido-PEG5-alcohol is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG5-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG5-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.