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MRL-871

Catalogue number:
HY-119464-100mg
Supplier:
Size:
100 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1392809-08-3

Purity:

99.11

Molecular Formula:

C22H12ClF3N2O3

Molecular Weight:

444.79

Mass Spectrometry:

Reference Materials

Product Description:

MRL-871 (compound 3) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 12.7 nM. MRL-871 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells[1].