Metopimazine
Catalogue number:
HY-116578-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
14008-44-7
Purity:
99.75
Molecular Formula:
C22H27N3O3S2
Molecular Weight:
445.60
Mass Spectrometry:
Reference Materials
Alternative Names:
EXP999; RP9965
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Metopimazine (EXP999; RP9965) is a phenothiazine, orally available, selective dopamine D2 receptor antagonist that does not penetrate the blood-brain barrier. Metopimazine blocks dopamine D2 receptors in the chemoreceptor trigger zone and the periphery, thereby inhibiting nausea and vomiting. Metopimazine is indicated for chemotherapy-induced nausea and vomiting, and has low central side effects due to its poor brain penetration. The use of metopimazine in acute gastroenteritis may have potential risks[1][2][3].