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(1R,2R)-Calhex 231 (hydrochloride)

Catalogue number:
HY-103320B-25mg
Supplier:
Size:
25 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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This product is for research use only and is not for human consumption or therapeutic use.
Purity:

99.07

Molecular Formula:

C25H28Cl2N2O

Molecular Weight:

443.41

Mass Spectrometry:

Reference Materials

Product Description:

(1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 µM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment[1][2].