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7-Chlorokynurenic acid (sodium salt)

Catalogue number:
HY-100811A-5mg
Supplier:
Size:
5 mg
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1263094-00-3

Purity:

99.89

Molecular Formula:

C10H5ClNNaO3

Molecular Weight:

245.59

Mass Spectrometry:

Reference Materials

Alternative Names:

7-CKA (sodium salt)

Product Description:

7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 µM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 µM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2].