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LDN-193189 (dihydrochloride)

Catalogue number:
HY-12071B-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1435934-00-1

Purity:

99.75

Molecular Formula:

C25H24Cl2N6

Molecular Weight:

479.40

Mass Spectrometry:

Reference Materials

Alternative Names:

DM-3189 (dihydrochloride)

Product Description:

LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3].