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MG-132

Catalogue number:
HY-13259-50mg
Supplier:
Size:
50 mg
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

133407-82-6

Purity:

99.97

Molecular Formula:

C26H41N3O5

Molecular Weight:

475.62

Mass Spectrometry:

Reference Materials

Alternative Names:

Z-Leu-Leu-Leu-al; MG132

Product Description:

MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC50s of 100 nM and 1.2 µM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis[1][2][3].