Alosetron (Hydrochloride)
Catalogue number:
HY-70050C-10mg
Supplier:
Size:
10 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
122852-69-1
Purity:
99.63
Molecular Formula:
C17H19ClN4O
Molecular Weight:
330.81
Mass Spectrometry:
Reference Materials
Alternative Names:
GR 68755C; GR 68755 (Hydrochloride); GR 68755X (Hydrochloride)
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- Protocol: View or download
Product Description:
Alosetron Hydrochloride (GR 68755C) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride is used for the research of irritable bowel syndrome (IBS). Alosetron blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects[1][2].