Thioacetamide
Catalogue number:
HY-Y0698-1g
Supplier:
Size:
1 g
Product is available in:
£46.00
Special price until 31 Dec 2025
Normal price £51.00
Shipping is calculated in checkout
Normal price £51.00
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
62-55-5
Purity:
98
Molecular Formula:
C2H5NS
Molecular Weight:
75.13
Alternative Names:
Acetothioamide; TAA; Thiacetamide
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model[1][2][3][4].