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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
95-71-6
Purity:
99.96
Molecular Formula:
C7H8O2
Molecular Weight:
124.14
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Methylhydroquinone is an orally active COX inhibitor with IC50s of 480.7 µM and 52.2 µM for ovine COX-1 and human recombinant COX-2, respectively. Methylhydroquinone has potential DNA damaging effects: 1) inhibiting COX-1 to reduce prostaglandin synthesis and exert anti-inflammatory activity; 2) inducing DNA single-strand breaks. Methylhydroquinone exerts its effects by competitively binding to the active sites of COX-1 (such as Tyr385, Met522) and non-covalent interactions[1][2]. 10mM