Selvigaltin
Catalogue number:
HY-147041-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1978336-95-6
Purity:
99.89
Molecular Formula:
C19H16BrF3N4O4S
Molecular Weight:
533.32
Mass Spectrometry:
Reference Materials
Alternative Names:
GB1211
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Selvigaltin (GB1211) is an orally active galectin-3 small molecule inhibitor with an IC50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci) and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (IL6, TGFβ3, SNAI2, collagen). Selvigaltin restores T-cell activity and induces less tumors and metastasis[1][2][3][4].