Narmafotinib
Catalogue number:
HY-145652-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1393653-34-3
Purity:
99.86
Molecular Formula:
C28H32F3N5O2
Molecular Weight:
527.58
Mass Spectrometry:
Reference Materials
Alternative Names:
AMP-945
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Narmafotinib (AMP-945) is an orally active inhibitor of the enzyme focal adhesion kinase (FAK, KD=0.21 nM). Narmafotinib inhibits autophosphorylation of 397Y-FAK in MDA-MB-231 cells with an IC50=7 nM and exhibits low general cellular toxicity (IC50=2.7 µM, MDA-MB-231 cells). Narmafotinib can be used for anti-cancer study[1].