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DNMT3A-IN-1

Catalogue number:
HY-144433-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1403598-56-0

Purity:

99.94

Molecular Formula:

C30H38N6O4

Molecular Weight:

546.66

Mass Spectrometry:

Reference Materials

Product Description:

DNMT3A-IN-1 (compound 1) is an effective and selective DNMT3A inhibitor. DNMT3A-IN-1 exhibits inhibitory activity against DNMT3A, with KI values ranging from 9.16 to 18.85 µM (AdoMet) and 11.37 to 23.34 µM (poly dI-dC). DNMT3A-IN-1 can induce apoptosis in acute myeloid leukemia (AML) cell lines (Apoptosis)[1][2].