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KR-39038

Catalogue number:
HY-143248-5mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£574.00 Special price until 31 Dec 2025
Normal price £637.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

2770300-35-9

Purity:

98.65

Molecular Formula:

C24H32ClFN6O

Molecular Weight:

475

Product Description:

KR-39038 is an orally active and potent GRK5 (G protein-coupled receptor kinase 5) inhibitor, with an IC50 of 0.02 µM. KR-39038 significantly inhibits angiotensin II-induced cellular hypertrophy through suppression of HDAC5 pathway in neonatal cardiomyocytes. KR-39038 shows profound anti-hypertrophic effects and improved cardiac function. KR-39038 can be used for heart failure research[1].