STAMBP-IN-1
Catalogue number:
HY-141852-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
896683-78-6
Purity:
98.73
Molecular Formula:
C27H28N4O4S
Molecular Weight:
504.60
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
STAMBP-IN-1 is a small-molecule inhibitor of STAMBP deubiquitinase, and interrupts STAMBP-Ub-NALP7 interaction. STAMBP-IN-1 decreases protein level of its inflammasome substrate NALP7 and suppresses IL-1b release after Toll-like receptor (TLR) agonism. STAMBP-IN-1 inhibits the activity of STAMBP to cleave recombinant di-Ub with an IC50 value of 0.33 mM[1].