Indirubin-3′-oxime
Catalogue number:
HY-139254-1mL
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
667463-82-3
Purity:
99.10
Molecular Formula:
C16H11N3O2
Molecular Weight:
277.28
Mass Spectrometry:
Reference Materials
Alternative Names:
IDR3O; I3O
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Indirubin-3′-oxime (IDR3O), a synthetic derivative of indirubin, is a potent inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Indirubin-3′-oxime directly inhibits the activity of all three isoforms of JNK (JNK1, JNK2, and JNK3), with IC50s of 0.8 µM, 1.4 µM, and 1.0 µM, respectively. Indirubin-3′-oxime can enhance height growth via activation of Wnt/β-catenin signaling in chondrocytes[1][2][3]. 10mM