DBCO-PEG4-VC-PAB-MMAE
Catalogue number:
HY-136314-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2129164-91-4
Purity:
99.18
Molecular Formula:
C88H128N12O19
Molecular Weight:
1658.03
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
DBCO-PEG4-VC-PAB-MMAE consists a ADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162). DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs). MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.