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(1S,2S)-Bortezomib

Catalogue number:
HY-135396-1mL
Supplier:
Size:
1 ml
Product is available in:
  • UK
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1132709-14-8

Purity:

96.0

Molecular Formula:

C19H25BN4O4

Molecular Weight:

384.24

Mass Spectrometry:

Reference Materials

Product Description:

(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a cell-permeable, reversible, and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki of 0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is an anti-cancer agent and the first therapeutic proteasome inhibitor to be used in humans[1][2][3]. 10mM