AFM-30a (hydrochloride)
Catalogue number:
HY-125099A-1mg
Supplier:
Size:
1 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
99.83
Molecular Formula:
C24H28ClFN6O3
Molecular Weight:
502.97
Mass Spectrometry:
Reference Materials
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
AFM-30a hydrochloride is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity. AFM-30a hydrochloride binds to PAD2 with an EC50 value of 9.5 µM. AFM-30a hydrochloride also inhibits H3 citrullination with an EC50 value of 0.4 µM. AFM-30a hydrochloride can be used for the research of certain cancers and a variety of autoimmune diseases including rheumatoid arthritis (RA), multiple sclerosis, lupus, and ulcerative colitis[1].