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TTA-A2

Catalogue number:
HY-111828-1mL
Supplier:
Size:
1 ml
£476.00
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This product is no longer available to order.
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

953778-63-7

Purity:

99.33

Molecular Formula:

C20H21F3N2O2

Molecular Weight:

378.39

Mass Spectrometry:

Reference Materials

Product Description:

TTA-A2 is a potent, selective and orally active t-type voltage gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy[1][2]. 10mM