Bezisterim
Catalogue number:
HY-108039-25mg
Supplier:
Size:
25 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1001100-69-1
Purity:
95.0
Molecular Formula:
C21H30O3
Molecular Weight:
330.46
Mass Spectrometry:
Reference Materials
Alternative Names:
HE 3286; NE-3107
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis[1][2][3]. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.