Alrizomadlin
Catalogue number:
HY-101518-100mg
Supplier:
Size:
100 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1818393-16-6
Purity:
98.67
Molecular Formula:
C34H38Cl2FN3O4
Molecular Weight:
642.59
Mass Spectrometry:
Reference Materials
Alternative Names:
APG-115; AA-115
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Alrizomadlin (APG-115) is an orally active MDM2 protein inhibitor binding to MDM2 protein with IC50 and Ki values of 3.8 nM and 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-dependent manner[2][3].