Liquiritin
Catalogue number:
HY-N0376-5mg
Supplier:
Size:
5 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
551-15-5
Purity:
99.99
Molecular Formula:
C21H22O9
Molecular Weight:
418.39
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- MSDS: View or download
- Protocol: View or download
Product Description:
Liquiritin, a flavonoid isolated from Glycyrrhiza uralensis, is a potent and competitive AKR1C1 inhibitor with IC50s of 0.62 µM, 0.61 µM, and 3.72µM for AKR1C1, AKR1C2 and AKR1C3, respectively. Liquiritin efficiently inhibits progesterone metabolism mediated by AKR1C1 in vivo[1]. Liquiritin acts as an antioxidant and has neuroprotective, anti-cancer and anti-inflammatory activity[2].