Tiratricol
Catalogue number:
HY-B1201-1mL
Supplier:
Size:
1 ml
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
51-24-1
Purity:
99.60
Molecular Formula:
C14H9I3O4
Molecular Weight:
621.93
Mass Spectrometry:
Reference Materials
Alternative Names:
3,3',5-Triiodothyroacetic acid
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
Tiratricol is an orally available thyroid hormone analog that inhibits pituitary thyroid-stimulating hormone secretion. Tiratricol is an intracellular toxin neutralizer that inhibits LPS and lipid A cytotoxicity with IC50s of 20 µM and 32 µM, respectively. Tiratricol reduces TNF production in lipopolysaccharide-stimulated macrophages. Tiratricol also has antiviral activity and is an inhibitor of yellow fever virus (Flavivirus). It can bind to the RdRp domain of the viral NS5 protein to hinder YFV replication.[2]. 10mM