GSK046
Catalogue number:
HY-136571-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2474876-09-8
Purity:
99.65
Molecular Formula:
C23H27FN2O4
Molecular Weight:
414.47
Mass Spectrometry:
Reference Materials
Alternative Names:
iBET-BD2
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
GSK046 (iBET-BD2), a chemical probe, is a potent, selective and orally active BD2 bromodomain inhibitor of the BET proteins, with IC50s of 264 nM (BRD2 BD2), 98 nM (BRD3 BD2), 49 nM (BRD4 BD2) and 214 nM (BRDT BD2), respectively. GSK046 has immunomodulatory activity[1].